---
title: "Principal Scientist, Analytical… – San Diego, CA"
canonical: "https://www.metaintro.com/job/principal-scientist-analytical-development-oligonucleotides-6c88c5d9-ce5e-5f7b-8bfc-ee8238ec9e8d"
language: "en"
author: "Metaintro"
---

[![Neurocrine Biosciences logo](/api/company-logo?url=https%3A%2F%2Fneurocrine.com%2Fapple-touch-icon.png&sig=UBqu-x2raNZ3ShUmecUMDNtXYP6mTT7rmJT8xxkzYPE)](/company/neurocrine-biosciences)[Neurocrine Biosciences](/company/neurocrine-biosciences)
# Principal Scientist, Analytical Development (Oligonucleotides, Bioconjugates) at Neurocrine Biosciences

Compensation · Listed in posting

$156,900 – $214,000/yr

**Setup**
: On-site

**Location**
: San Diego, California

**Type**
: Full-time

**Level**
: senior

**Posted**
: Sep 29, 2026

## Description

Neurocrine Biosciences is hiring an Analytical Development Scientist to lead analytical development for oligonucleotides and/or antibody oligo conjugates across preclinical through commercial drug substance and drug product development. The role covers method development, validation, qualification, transfer, control strategies, cGMP compliance, regulatory documentation, laboratory work, and cross-functional CMC support. Candidates need a relevant bachelor's, master's, or PhD degree and 4–8 years of experience, along with expertise in analytical chemistry, bioanalysis, bioprocessing, formulation, and modern characterization techniques. The position offers an annual base salary of $156,900–$214,000, a 30% target bonus, equity participation, and medical, dental, and vision benefits.

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