---
title: "Principal Software Engineer at Amgen – Tampa, FL +1"
canonical: "https://www.metaintro.com/job/principal-software-engineer-at-amgen-01ab289d-1bc0-5149-80fc-7293c58adde1"
language: "en"
author: "Metaintro"
---

[![Amgen logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.google.com%2Fs2%2Ffavicons%3Fdomain%3Dwww.amgen.com%26sz%3D128)](/company/amgen)[Amgen](/company/amgen)
# Principal Software Engineer at Amgen

Compensation · Listed in posting

$157,021 – $212,440/yr

**Location**
: Tampa, Florida · Thousand Oaks, California

**Type**
: Full-time

**Level**
: lead/mgmt

**Posted**
: Jun 10, 2026

## Description

Amgen is hiring a Principal Software Engineer to lead the end-to-end design, development, and production deployment of machine learning and Generative AI solutions, including agentic AI systems, MLOps/LLMOps platforms, scalable cloud architectures, evaluation and governance frameworks, and data platforms. The role requires deep expertise in machine learning, deep learning, and Generative AI, along with experience leading large-scale initiatives and mentoring L4 and L5 engineers. The position offers a U.S. annual salary range of 157,020.50 to 212,439.50 USD and includes health, dental, vision, retirement, bonus, stock-based, and flexible work benefits.

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