---
title: "Sr. Machine Learning Engineer - Machine… – Watertown, MA"
canonical: "https://www.metaintro.com/job/sr-machine-learning-engineer-machine-learning-at-dyno-therapeutics-0aed0ec3-0b93-5019-b549-347f381d15c2"
language: "en"
author: "Metaintro"
---

[/company/dyno-therapeutics](/company/dyno-therapeutics)[Dyno Therapeutics](/company/dyno-therapeutics)
# Sr. Machine Learning Engineer - Machine Learning at Dyno Therapeutics

Department: Machine Learning

Compensation

$178,662 – $213,680/yr

**Setup**
: Remote

**Location**
: Watertown, Massachusetts

**Type**
: Full-time

**Level**
: senior

**Posted**
: Aug 18, 2026

## Description

Dyno Therapeutics is hiring a senior machine learning engineer to build and scale machine learning infrastructure, training and inference systems, performance optimization tools, and agentic AI workflows supporting protein design and AI-driven genetic medicine research. The role collaborates with AI scientists, protein engineers, and ML engineers, and requires strong software engineering, containerization, distributed computing, GPU performance engineering, and complex systems ownership. It is full-time, based in Watertown, Massachusetts, or remote, with a base salary of $178,662.29–$213,680.10 per year plus bonus, equity, insurance, retirement, paid time off, and other benefits.

## Trending job searches

Every query opens live roles, salary samples, and market demand — tap a search to run it instantly.

- [Find Sr. Machine Learning Engineer - Machine Learning jobs in Watertown, Massachusetts, United States](/jobs/search?q=Find+Sr.+Machine+Learning+Engineer+-+Machine+Learning+jobs+in+Watertown%2C+Massachusetts%2C+United+States)
- [Find roles similar to Sr. Machine Learning Engineer - Machine Learning in Watertown, Massachusetts, United States](/jobs/search?q=Find+roles+similar+to+Sr.+Machine+Learning+Engineer+-+Machine+Learning+in+Watertown%2C+Massachusetts%2C+United+States)
- [Find remote Sr. Machine Learning Engineer - Machine Learning jobs](/jobs/search?q=Find+remote+Sr.+Machine+Learning+Engineer+-+Machine+Learning+jobs)
- [Find Sr. Machine Learning Engineer - Machine Learning jobs with Software engineering and Docker](/jobs/search?q=Find+Sr.+Machine+Learning+Engineer+-+Machine+Learning+jobs+with+Software+engineering+and+Docker)
- [Find jobs similar to Sr. Machine Learning Engineer - Machine Learning](/jobs/search?q=Find+jobs+similar+to+Sr.+Machine+Learning+Engineer+-+Machine+Learning)
- [Find Sr. Machine Learning Engineer - Machine Learning jobs posted this week](/jobs/search?q=Find+Sr.+Machine+Learning+Engineer+-+Machine+Learning+jobs+posted+this+week)
- [Find Sr. Machine Learning Engineer - Machine Learning jobs paying $170,000 or more per year](/jobs/search?q=Find+Sr.+Machine+Learning+Engineer+-+Machine+Learning+jobs+paying+%24170%2C000+or+more+per+year)
- [Find Artificial Intelligence/Machine Learning jobs in Watertown, Massachusetts, United States](/jobs/search?q=Find+Artificial+Intelligence%2FMachine+Learning+jobs+in+Watertown%2C+Massachusetts%2C+United+States)

## Get More from Metaintro

Unlock powerful job search, personalized recommendations, and deep career insights from comprehensive, market-leading data and live market signals.

- [Browse all jobs](/jobs/search)
- [Access help center](/help)
- [Explore our content](/blog)

![](https://cdn.metaintro.com/rs:fill:1200:800/q:30/plain/images/bridges/bridge-expand.1df895c6bd76d96f.png)

For job seekers

## Ready to find a role that actually fits?

Upload your résumé, start a Job Search Thread, and let Metaintro rank real openings against your experience — then guide you from search to offer.

[Get Started Free](/signup)[Search matching jobs](/jobs/search)

Match

Compare live roles against your current evidence.

Position

Turn proof projects into role-specific applications.

Improve

Use market feedback to keep the skill plan current.

[Return to navigation](#main-navigation)