---
title: "Supervisor, Manufacturing Operations… at vrtx – Boston, MA"
canonical: "https://www.metaintro.com/job/supervisor-manufacturing-operations-2nd-shift-2b-at-vrtx-e10367a0-c98f-5ccd-b004-94367e1203b6"
language: "en"
author: "Metaintro"
---

[/company/vrtx](/company/vrtx)[vrtx](/company/vrtx)
# Supervisor, Manufacturing Operations 2nd shift (2B) at vrtx

Compensation · Listed in posting

$97,900 – $146,900/yr

**Location**
: Boston, Massachusetts

**Type**
: Full-time

**Level**
: lead/mgmt

**Posted**
: Sep 21, 2026

## Description

Vertex is hiring an on-site Supervisor, Manufacturing Operations to lead first-, second-, or third-shift manufacturing activities in a drug-product facility. The role assigns work from production schedules, oversees cGMP operations including equipment setup, assembly, operation, disassembly, and cleaning, reviews batch records, enforces GMP compliance, and coordinates with cross-functional teams. It requires a bachelor’s degree in a scientific, technical, or engineering discipline and 6+ years of experience or equivalent education and experience, with preferred supervisory, cell-therapy, aseptic manufacturing, and POMS MES experience. The position follows a Tuesday-through-Saturday afternoon/evening schedule, is designated on-site, and pays $97,900–$146,900 annually.

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