--- title: "Nurse Practitioner Jobs in Charleston, SC | Metaintro" canonical: "https://www.metaintro.com/jobs/nurse-practitioner/locations/charleston-sc" language: "en" author: "Metaintro" data_as_of: "2026-11-04T04:40:12.367Z" cite_as: "Metaintro job-market data. https://www.metaintro.com/jobs/nurse-practitioner/locations/charleston-sc" data: ["https://www.metaintro.com/jobs/nurse-practitioner/locations/charleston-sc/data.json"] --- Nurse Practitioner market brief · Charleston, SC # Nurse Practitioner Jobs in Charleston, SC 55 nurse practitioner openings are live in the Charleston, SC area from 23 employers, led by MUSC, Restore Hyper Wellness, and Matrix Medical Network. 9% of listings accept remote work. Data updated Nov 4, 2026 [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Charleston%2C+SC)[Browse all Nurse Practitioner markets](/jobs/nurse-practitioner) ## Role and market snapshot A quick read on demand before you open the live listings **Tracked jobs** : 55 : Live nurse practitioner openings currently tracked in the Charleston market. **Companies hiring** : 23 : Distinct employers represented in this publishable market view. **Median compensation** : Not published : Not enough employers here disclose pay to publish a local median, so none is shown. ## Market analysis Role-specific demand, level, employer, and compensation signals for this local market Start with the level mix, then compare current demand, compensation coverage, and employer concentration before opening the live listings. Level mix ### Career ladder [Entry-level](/jobs/nurse-practitioner/locations/charleston-sc/entry-level)20 jobs Lead+1 jobs Level coverage is 38%. Counts remain visible, but fit guidance stays withheld until at least 60% of listings have a reliable level signal. 30-day window ### Demand and salary Current jobs 55 Hiring employers 23 Salary coverage 29% Median experience 2.0 years Within this market ### Employer tier lens Startups & growing teams 39 11 companies · $111,950 median Established employers 7 6 companies Use Metaintro ### Turn this market signal into momentum Move from aggregate demand to the live roles hiring in this market now. - Open live nurse practitioner listings in Charleston - Compare the level mix before narrowing your search - Use employer and compensation signals to prioritize outreach [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Charleston%2C+SC)[Get started free](/signup) ## Turn this market brief into a live search. Use the signal The best next step is opening the roles behind the aggregate: compare nurse practitioner opportunities in Charleston, save the strongest fits, and keep the market signal close while you apply. - 55 live roles tracked in this market. - 23 employers represented in the current window. - Market data refreshed Nov 4, 2026. [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Charleston%2C+SC)[Compare other markets](/jobs/nurse-practitioner) ## A practical market plan for Nurse Practitioner in Charleston Use this sequence to move from aggregate labor-market data to a focused application list. 1. 01Read the demand 55 nurse practitioner openings across 23 employers establish the current Charleston opportunity set. 2. 02Choose the right rung Use the live listings to calibrate title, scope, and experience expectations before applying. 3. 03Prioritize employers MUSC is one of the most active visible employers, with 16 current openings in this market view. 4. 04Open the live roles 24 representative openings connect this brief to jobs you can review now. With Metaintro Keep market research, live opportunities, saved roles, and the evidence behind your applications moving in one focused loop. ## Where this market is hiring Move from the Charleston market view into active employers and representative nurse practitioner openings Employer activity · 23 companies ### Who is hiring in this market The most active visible employers, ordered by openings represented in the current market sample. [![MUSC logo](/api/company-logo?url=https%3A%2F%2Fd3crna64wemw02.cloudfront.net%2Fasset%2F339713052848%2Fimage_mm92lu8uqd1pl64qa937agao1n%2F%3Fcontent-disposition%3Dinline&sig=_Ppad97Sg8J2ZU82krF9CiJg0lqlAIcbhILT4KgPnlA) MUSCStartups & growing teams16Open roles](/company/musc)[![Restore Hyper Wellness logo](/api/company-logo?url=https%3A%2F%2Fcdn.prod.website-files.com%2F615f535b3d97e2228b7fbce6%2F616f0ebbbd2595a037ff6d77_Favicon-Webclip-256.png&sig=Xy28WvVpV9Fg-nz8DIqMil6rN0BA94--6wnDNaQbapI) Restore Hyper WellnessStartups & growing teams6Open roles](/company/restore-hyper-wellness)[![Matrix Medical Network logo](/api/company-logo?url=https%3A%2F%2Fwww.matrixmedicalnetwork.com%2Fwp-content%2Fuploads%2F2024%2F09%2Fcropped-blue_logo-180x180.png&sig=sHxlxvjjDJpaGbVP5_z9Kp_SxDDcZMTzmyKO1-RllE4) Matrix Medical NetworkStartups & growing teams4Open roles](/company/matrix-medical-network)[![NakedMD logo](/api/company-logo?url=https%3A%2F%2Fwww.nakedmd.com%2Fcdn%2Fshop%2Ffiles%2Ffavi.webp%3Fcrop%3Dcenter%26height%3D32%26v%3D1680046566%26width%3D32&sig=Dk_bxMHyS6I4iu-0VlxPcTS1ALlEC0anHb1ikYTYFLw) NakedMDStartups & growing teams3Open roles](/company/nakedmd)[![Charleston Oncology logo](/api/company-logo?url=https%3A%2F%2Fcdn-jpcoj.nitrocdn.com%2FUmpvDuoizrfLWpLCUXnJDLpjblEtXksP%2Fassets%2Fimages%2Foptimized%2Frev-1e45139%2Fwww.charlestononcology.com%2Fwp-content%2Fuploads%2F2021%2F09%2Fchas-oncology-fav-150x150.png&sig=srIDarqsLGWZirTDsOsWUyOdciOOsX5isN3856feQmY) Charleston OncologyStartups & growing teams2Open roles](/company/charleston-oncology)[![Curana Health logo](/api/company-logo?url=https%3A%2F%2Fcuranahealth.com%2Fwp-content%2Fuploads%2F2025%2F10%2Fcropped-Curana-Health-Favicon-180x180.webp&sig=WZYi8Rz1N5fTH17DhOoVJDV78OjRPfoiXRn6R1vmcKo) Curana HealthTop of market2Open roles](/company/curana-health)[![CVS Health logo](/api/company-logo?url=https%3A%2F%2Fcvshealth.com%2Ffavicon.ico&sig=hlTkPCEuEh6YBrjgHMqtjATETTGXksXNFBXbFDPamw0) CVS HealthStartups & growing teams2Open roles](/company/cvs-health)[![LifeStance logo](/api/company-logo?url=https%3A%2F%2Flifestance.com%2Fwp-content%2Fthemes%2Flifestance-sage11%2Fpublic%2Fbuild%2Fassets%2Fapple-icon-180x180-Co5-cuID.png&sig=S0fV3R3Gg_Nj5hNt7cgd1GJgVKWL__7IKVzUQndXyOw) LifeStanceStartups & growing teams2Open roles](/company/lifestance) Live opportunity sample · 24 of 55 matches ### Representative openings Open a role to inspect the full requirements. Compensation appears only when the listing provides usable salary data. [Psychiatric Nurse Practitioner (PMHNP) - Child/AdolescentLive roleLifeStanceCharleston, South Carolina$142,000Posted Nov 2, 2026](/job/psychiatric-nurse-practitioner-pmhnp-child-adolescent-at-lifestance-29e726af-6b41-5bd8-b160-00937ef8548a)[Nurse Practitioner or Physician Assistant - HemOnc InfusionLive roleMUSCCharleston, South CarolinaPosted Oct 30, 2026](/job/nurse-practitioner-or-physician-assistant-hemonc-infusion-at-musc-32925a0b-7bd7-5c16-99d6-1c571b6ee898)[Nurse Practitioner / Physician Assistant (FT or PT)Live roleWest Coast WoundCharleston, South CarolinaPosted Oct 29, 2026](/job/nurse-practitioner-physician-assistant-ft-or-pt-at-west-coast-wound-41312666-6ab9-5d02-bcb6-79a9cb1df387)[Psychiatric Nurse Practitioner (PMHNP) - Child/AdolescentLive roleLifeStanceNorth Charleston, South Carolina$142,000Posted Oct 23, 2026](/job/psychiatric-nurse-practitioner-pmhnp-child-adolescent-at-lifestance-eb783d52-175a-5a61-a872-3d0a953aa80a)[Nurse Practitioner or Physician Assistant - Child & Adolescent PsychiatryEntry-levelMUSCCharleston, South CarolinaPosted Oct 23, 2026](/job/nurse-practitioner-or-physician-assistant-child-and-adolescent-1af54021-6ccc-5466-bb11-8c943e5b84b0)[In-Home Nurse Practitioner or Physician Assistant Full Time - Charleston (Jackson County)Live roleCVS HealthCharleston, South Carolina$78,331Posted Oct 22, 2026](/job/in-home-nurse-practitioner-or-physician-assistant-full-time-fb70065b-dd96-55e5-8122-11b22bd54ce8)[Nurse Practitioner or Physician Assistant - Hematology OncologyLive roleMUSCCharleston, South CarolinaPosted Oct 22, 2026](/job/nurse-practitioner-or-physician-assistant-hematology-oncology-at-musc-816307a3-9c29-5e33-90c2-4e326e8d2036)[Urgent Care Nurse Practitioner or Physician Assistant- Charleston, SCLive roleWEL1014WELSNorth Charleston, South CarolinaPosted Oct 21, 2026](/job/urgent-care-nurse-practitioner-or-physician-assistant-charleston-sc-6ad0e1c6-a722-50f8-bebb-e7c9408ebab8) #### More nurse practitioner openings in Charleston - [Urgent Care Nurse Practitioner or Physician Assistant- Charleston, SC · Prisma Health UC by Wellstreet, LLC](/job/urgent-care-nurse-practitioner-or-physician-assistant-charleston-sc-2732ea34-44f0-592b-b2c0-8f5b387eb888) - [Nurse Practitioner – Hematology/Oncology with BMT & Cellular Therapy Focus · Charleston Oncology](/job/nurse-practitioner-hematology-oncology-with-bmt-and-cellular-therapy-83e902c6-8148-5e5f-8fbc-57cfbbe26afe) - [Telehealth: Psychiatric Mental Health Nurse Practitioner (PMHNP) · Seasoned Recruitment](/job/telehealth-psychiatric-mental-health-nurse-practitioner-pmhnp-at-a2479a82-8987-55b0-8c26-a06d28f8f84b) - [Nurse Practitioner or Physician Assistant - Acute Care Surgery · MUSC](/job/nurse-practitioner-or-physician-assistant-acute-care-surgery-at-musc-a15dab85-ffe0-5527-8b4d-d877dd1d44c8) - [Urgent Care Nurse Practitioner or Physician Assistant- Mt. Pleasant, SC · WEL1014WELS](/job/urgent-care-nurse-practitioner-or-physician-assistant-mt-pleasant-sc-c8bd835c-b2ed-54ef-af02-d1b3bf0ac992) - [Urgent Care Nurse Practitioner or Physician Assistant- Mt. Pleasant, SC · Prisma Health UC by Wellstreet, LLC](/job/urgent-care-nurse-practitioner-or-physician-assistant-mt-pleasant-sc-db07402e-9edf-5ef6-ae08-e3104f38e251) - [Nurse Practitioner, Advanced Practice Provider · CVS Health](/job/nurse-practitioner-advanced-practice-provider-at-cvs-health-eb4cc5ef-3e99-5033-877a-fa179c98f3be) - [Nurse Practitioner or Physician Assistant - Hospital Medicine · MUSC](/job/nurse-practitioner-or-physician-assistant-hospital-medicine-at-musc-271257c6-2efa-543a-986e-2afadfa1dd5a) - [Nurse Practitioner or Physician Assistant PRN · Concentra](/job/nurse-practitioner-or-physician-assistant-prn-at-concentra-dd4ff3a2-ca37-55d0-8ab1-fa25c9f63bcb) - [Nurse Practitioner (NP) Weekends · ACG Hospice](/job/nurse-practitioner-np-weekends-at-acg-hospice-4e20e15c-4945-59b3-b734-2f3386e45dab) - [Nurse Practitioner or Physician Assistant - Internal Medicine Primary Care · MUSC](/job/nurse-practitioner-or-physician-assistant-internal-medicine-primary-0d6098fe-b04e-5807-8287-5e78cdc3d41c) - [Nurse Practitioner or Physician Assistant - Pediatrics Hematology & Oncology · MUSC](/job/nurse-practitioner-or-physician-assistant-pediatrics-hematology-and-c1d09270-faeb-5041-aed2-f4e7949df9a3) - [Nurse Practitioner or Physician Assistant - Primary Care · MUSC](/job/nurse-practitioner-or-physician-assistant-primary-care-at-musc-04e6c755-39d5-5303-90ed-78477a64851f) - [Nurse Practitioner (PRN) - In-Home Health Assessments · Matrix Medical Network](/job/nurse-practitioner-prn-in-home-health-assessments-at-matrix-medical-e6305851-c670-5ce1-8a3c-3581b6191572) - [Nurse Practitioner (PRN) - In-Home Health Assessments · Matrix Medical Network](/job/nurse-practitioner-prn-in-home-health-assessments-at-matrix-medical-b65c7130-3151-560b-a0d0-74834b60e8f9) - [Nurse Practitioner (PRN) - In-Home Health Assessments · Matrix Medical Network](/job/nurse-practitioner-prn-in-home-health-assessments-at-matrix-medical-61b00cf0-1114-5acd-8075-700349430a07) [Explore all 55 matching jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Charleston%2C+SC) ## Nurse Practitioner jobs in Charleston: what applicants need to know Current answers for a difficult AI-era job search, grounded in this publishable role and location market view rather than generic career advice. 1. 01### How many nurse practitioner jobs are open in Charleston? Metaintro tracks 55 live nurse practitioner openings from 23 employers in the Charleston, SC area over the last 30 days. 2. 02### Which companies are hiring for nurse practitioner jobs in Charleston? MUSC, Restore Hyper Wellness, Matrix Medical Network, and NakedMD have the most open nurse practitioner roles here right now, out of 23 hiring employers. ## Continue with the next market signal Compare nearby cities, adjacent roles, and publishable level views without leaving the live jobs cluster Nearby cities Compare Nurse Practitioner demand around Charleston. [Savannah, GA](/jobs/nurse-practitioner/locations/savannah-ga)[Columbia, SC](/jobs/nurse-practitioner/locations/columbia-sc)[Wilmington, NC](/jobs/nurse-practitioner/locations/wilmington-nc)[Fayetteville, NC](/jobs/nurse-practitioner/locations/fayetteville-nc)[Charlotte, NC](/jobs/nurse-practitioner/locations/charlotte-nc)[Jacksonville, FL](/jobs/nurse-practitioner/locations/jacksonville-fl) Related roles See adjacent role demand in the Charleston market. [Physician Assistant](/jobs/physician-assistant/locations/charleston-sc)[Nurse](/jobs/nurse/locations/charleston-sc)[Pharmacist](/jobs/pharmacist/locations/charleston-sc)[All roles in Charleston](/jobs/locations/charleston-sc) Level views Narrow the market to experience levels with enough reliable data. [Entry-level Nurse Practitioner](/jobs/nurse-practitioner/locations/charleston-sc/entry-level) Built for career movement ## Turn the Charleston nurse practitioner market into your next move. Use live demand, employer, level, and compensation signals to focus your nurse practitioner search where the market is active now. [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Charleston%2C+SC)[Get started free](/signup) - MatchCompare live roles against your current evidence. - PositionTurn proof projects into role-specific applications. - ImproveUse market feedback to keep the skill plan current. [Return to navigation](#main-navigation)