--- title: "Nurse Practitioner Jobs in Columbia, SC | Metaintro" canonical: "https://www.metaintro.com/jobs/nurse-practitioner/locations/columbia-sc" language: "en" author: "Metaintro" data_as_of: "2026-11-04T04:30:12.144Z" cite_as: "Metaintro job-market data. https://www.metaintro.com/jobs/nurse-practitioner/locations/columbia-sc" data: ["https://www.metaintro.com/jobs/nurse-practitioner/locations/columbia-sc/data.json"] --- Nurse Practitioner market brief · Columbia, SC # Nurse Practitioner Jobs in Columbia, SC 107 nurse practitioner openings are live in the Columbia, SC area from 23 employers, led by PrismaHealth, Lexington Medical Center, and Prisma Health UC by Wellstreet, LLC. Data updated Nov 5, 2026 [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Columbia%2C+SC)[Browse all Nurse Practitioner markets](/jobs/nurse-practitioner) ## Role and market snapshot A quick read on demand before you open the live listings **Tracked jobs** : 107 : Live nurse practitioner openings currently tracked in the Columbia market. **Companies hiring** : 23 : Distinct employers represented in this publishable market view. **Median compensation** : Not published : Not enough employers here disclose pay to publish a local median, so none is shown. ## Market analysis Role-specific demand, level, employer, and compensation signals for this local market Start with the level mix, then compare current demand, compensation coverage, and employer concentration before opening the live listings. Level mix ### Career ladder [Entry-level](/jobs/nurse-practitioner/locations/columbia-sc/entry-level)32 jobs Mid-level2 jobs Lead+1 jobs Level coverage is 33%. Counts remain visible, but fit guidance stays withheld until at least 60% of listings have a reliable level signal. 30-day window ### Demand and salary Current jobs 107 Hiring employers 23 Salary coverage 15% Median experience 1.0 years Within this market ### Employer tier lens Established employers 56 5 companies Startups & growing teams 17 11 companies · $124,800 median Use Metaintro ### Turn this market signal into momentum Move from aggregate demand to the live roles hiring in this market now. - Open live nurse practitioner listings in Columbia - Compare the level mix before narrowing your search - Use employer and compensation signals to prioritize outreach [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Columbia%2C+SC)[Get started free](/signup) ## Turn this market brief into a live search. Use the signal The best next step is opening the roles behind the aggregate: compare nurse practitioner opportunities in Columbia, save the strongest fits, and keep the market signal close while you apply. - 107 live roles tracked in this market. - 23 employers represented in the current window. - Market data refreshed Nov 5, 2026. [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Columbia%2C+SC)[Compare other markets](/jobs/nurse-practitioner) ## A practical market plan for Nurse Practitioner in Columbia Use this sequence to move from aggregate labor-market data to a focused application list. 1. 01Read the demand 107 nurse practitioner openings across 23 employers establish the current Columbia opportunity set. 2. 02Choose the right rung Use the live listings to calibrate title, scope, and experience expectations before applying. 3. 03Prioritize employers PrismaHealth is one of the most active visible employers, with 51 current openings in this market view. 4. 04Open the live roles 24 representative openings connect this brief to jobs you can review now. With Metaintro Keep market research, live opportunities, saved roles, and the evidence behind your applications moving in one focused loop. ## Where this market is hiring Move from the Columbia market view into active employers and representative nurse practitioner openings Employer activity · 23 companies ### Who is hiring in this market The most active visible employers, ordered by openings represented in the current market sample. [![PrismaHealth logo](/api/company-logo?url=https%3A%2F%2Fprismahealth.org%2Fapple-touch-icon.png&sig=CrTyHCNcMqodqIZlHQuIcvbb3WasH3yIJkIc_l_VmIk) PrismaHealthEstablished employers51Open roles](/company/prismahealth)![Lexington Medical Center logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.google.com%2Fs2%2Ffavicons%3Fdomain%3Dlexingtonmedicalcenter.com%26sz%3D128) Lexington Medical CenterEmployer profile19Open roles Prisma Health UC by Wellstreet, LLCEmployer profile5Open roles Prisma Health-UpstateEmployer profile4Open roles [![LifeStance logo](/api/company-logo?url=https%3A%2F%2Flifestance.com%2Fwp-content%2Fthemes%2Flifestance-sage11%2Fpublic%2Fbuild%2Fassets%2Fapple-icon-180x180-Co5-cuID.png&sig=S0fV3R3Gg_Nj5hNt7cgd1GJgVKWL__7IKVzUQndXyOw) LifeStanceStartups & growing teams3Open roles](/company/lifestance)[![UnitedHealth Group logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.unitedhealthgroup.com%2Fapps%2Fuhg%2Fclientlibs%2Fresources%2Fimages%2Fuhg-logo.png) UnitedHealth GroupStartups & growing teams3Open roles](/company/unitedhealth) WEL1014WELSEmployer profile3Open roles [![MUSC logo](/api/company-logo?url=https%3A%2F%2Fd3crna64wemw02.cloudfront.net%2Fasset%2F339713052848%2Fimage_mm92lu8uqd1pl64qa937agao1n%2F%3Fcontent-disposition%3Dinline&sig=_Ppad97Sg8J2ZU82krF9CiJg0lqlAIcbhILT4KgPnlA) MUSCStartups & growing teams2Open roles](/company/musc) Live opportunity sample · 24 of 107 matches ### Representative openings Open a role to inspect the full requirements. Compensation appears only when the listing provides usable salary data. [Psychiatric Nurse Practitioner (PMHNP) - Child/AdolescentLive roleLifeStanceColumbia, South Carolina$142,000Posted Nov 2, 2026](/job/psychiatric-nurse-practitioner-pmhnp-child-adolescent-at-lifestance-63dba10e-8f45-5268-ab75-272f838d523f)[Nurse Practitioner - Lexington HospitalistLive roleLexington Medical CenterWest Columbia, South CarolinaPosted Oct 30, 2026](/job/nurse-practitioner-lexington-hospitalist-at-lexington-medical-center-65f2cd40-7780-5532-957e-16f8359aad2b)[Nurse Practitioner - Care at Home - South Carolina Statewide TravelerLive roleUnitedHealth GroupColumbia, South Carolina$109,500Posted Oct 29, 2026](/job/nurse-practitioner-care-at-home-south-carolina-statewide-traveler-at-436af28c-f3e7-5d85-bf62-d1323761d6ee)[Nurse PractitionerEntry-levelPruittHealthColumbia, South CarolinaPosted Oct 28, 2026](/job/nurse-practitioner-at-pruitthealth-d11889c2-199c-5f99-a438-5f69561524ea)[Nurse Practitioner - Northeast Columbia Infusion CenterEntry-levelOption Care HealthColumbia, South Carolina$92,004Posted Oct 28, 2026](/job/nurse-practitioner-northeast-columbia-infusion-center-at-option-care-fac7286a-fb47-599d-a8ae-5fce3d6add84)[Nurse PractitionerEntry-levelPruittHealthColumbia, South CarolinaPosted Oct 28, 2026](/job/nurse-practitioner-at-pruitthealth-18253f34-f64d-54cc-bd87-7c313f970ddc)[Nurse PractitionerLive roleLexington Medical CenterLexington, South CarolinaPosted Oct 26, 2026](/job/nurse-practitioner-at-lexington-medical-center-33928bf5-f3ab-591b-880d-558ac5b2f08c)[Psychiatric Mental Health Nurse Practitioner (PMHNP)Live roleLifeStanceColumbia, South Carolina$142,000Posted Oct 26, 2026](/job/psychiatric-mental-health-nurse-practitioner-pmhnp-at-lifestance-20e0c887-8715-58e8-bde5-8f96b5ff7690) #### More nurse practitioner openings in Columbia - [Nurse Practitioner · Milan Laser Hair Removal](/job/nurse-practitioner-at-milan-laser-hair-removal-2a32790a-03f2-5f4b-b038-b3921d780da1) - [Nurse Practitioner / Physician Assistant - Pulmonology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-02c96bd4-a49d-5eb9-8be8-d4e4fd798875) - [Nurse Practitioner / Physician Assistant - Pulmonology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-104b0cbe-add4-5904-bc57-cca06e48fb19) - [Advanced Practice Provider | Neonatal Nurse Practitioner (NNP)| MUSC Health Columbia Medical Center Northeast - Columbia, SC · MUSC](/job/advanced-practice-provider-neonatal-nurse-practitioner-nnp-musc-76031e00-a428-5fe0-8f32-4ce594f3a7dc) - [Nurse Practitioner / Physician Assistant - Pulmonology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-a8d082e9-5024-5d49-8d53-785404e90de7) - [Nurse Practitioner / Physician Assistant - Pulmonology - Columbia · Prisma Health-Upstate](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-prisma-244d1a32-a79e-5881-8761-d8fa1d958a7f) - [Nurse Practitioner, Regional Traveler-PA, DE, NC, SC and GA · UnitedHealth Group](/job/nurse-practitioner-regional-traveler-pa-de-nc-sc-and-ga-at-0a8d0a6d-0923-5b0a-a8e0-49a6e003da40) - [Nurse Practitioner or Physician Assistant- Primary Care - Optum/Colonial Healthcare · UnitedHealth Group](/job/nurse-practitioner-or-physician-assistant-primary-care-optum-colonial-350221f1-7a8c-5296-b1e6-8755ac471ccc) - [Nurse Practitioner (CMC) · Lexington Medical Center](/job/nurse-practitioner-cmc-at-lexington-medical-center-360c3e79-8a71-5cc7-bb51-8038116e1cbb) - [Nurse Practitioner (CMC) · Lexington Medical Center](/job/nurse-practitioner-cmc-at-lexington-medical-center-617dd9b9-a52c-588d-8ad6-4fae221ed25e) - [Nurse Practitioner Columbia, SC $135K · Nirvana Healthcare](/job/nurse-practitioner-columbia-sc-135k-at-private-family-office-6186a790-f406-5330-8cc0-6467ffbc82c7) - [Nurse Practitioner Family $500- $600/Day Full Time Or Part Time, Columbia, SC · Nirvana Healthcare](/job/nurse-practitioner-family-500-600-day-full-time-or-part-time-columbia-0b378abd-94bf-5524-8c59-1225fbe27f7e) - [Family Nurse Practitioner · A-Line Staffing Solutions](/job/family-nurse-practitioner-at-a-line-staffing-solutions-8496b8aa-e354-5fb7-b97b-a6dba5b12a78) - [Urgent Care Nurse Practitioner or Physician Assistant- Columbia, SC (Float) · WEL1014WELS](/job/urgent-care-nurse-practitioner-or-physician-assistant-columbia-sc-546b27b4-2ed7-516f-a970-b58645dab256) - [Urgent Care Nurse Practitioner or Physician Assistant- Columbia, SC (Float) · Prisma Health UC by Wellstreet, LLC](/job/urgent-care-nurse-practitioner-or-physician-assistant-columbia-sc-c904f246-7eb4-560e-8510-b65668ce06a9) - [Nurse Practitioner / Physician Assistant - Urology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-urology-columbia-at-dab3b272-d54a-5c5c-86ef-733c554a115b) [Explore all 107 matching jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Columbia%2C+SC) ## Nurse Practitioner jobs in Columbia: what applicants need to know Current answers for a difficult AI-era job search, grounded in this publishable role and location market view rather than generic career advice. 1. 01### How many nurse practitioner jobs are open in Columbia? Metaintro tracks 107 live nurse practitioner openings from 23 employers in the Columbia, SC area over the last 30 days. 2. 02### Which companies are hiring for nurse practitioner jobs in Columbia? PrismaHealth, Lexington Medical Center, Prisma Health UC by Wellstreet, LLC, and Prisma Health-Upstate have the most open nurse practitioner roles here right now, out of 23 hiring employers. ## Continue with the next market signal Compare nearby cities, adjacent roles, and publishable level views without leaving the live jobs cluster Nearby cities Compare Nurse Practitioner demand around Columbia. [Charlotte, NC](/jobs/nurse-practitioner/locations/charlotte-nc)[Charleston, SC](/jobs/nurse-practitioner/locations/charleston-sc)[Savannah, GA](/jobs/nurse-practitioner/locations/savannah-ga)[Athens, GA](/jobs/nurse-practitioner/locations/athens-ga)[Asheville, NC](/jobs/nurse-practitioner/locations/asheville-nc)[Fayetteville, NC](/jobs/nurse-practitioner/locations/fayetteville-nc) Related roles See adjacent role demand in the Columbia market. [Physician Assistant](/jobs/physician-assistant/locations/columbia-sc)[Nurse](/jobs/nurse/locations/columbia-sc)[Pharmacist](/jobs/pharmacist/locations/columbia-sc)[All roles in Columbia](/jobs/locations/columbia-sc) Level views Narrow the market to experience levels with enough reliable data. [Entry-level Nurse Practitioner](/jobs/nurse-practitioner/locations/columbia-sc/entry-level) Built for career movement ## Turn the Columbia nurse practitioner market into your next move. Use live demand, employer, level, and compensation signals to focus your nurse practitioner search where the market is active now. [Search live jobs](/jobs/search?q=Nurse+Practitioner+jobs+in+Columbia%2C+SC)[Get started free](/signup) - MatchCompare live roles against your current evidence. - PositionTurn proof projects into role-specific applications. - ImproveUse market feedback to keep the skill plan current. [Return to navigation](#main-navigation)