---
title: "Nurse Jobs in Columbia, SC | Metaintro"
canonical: "https://www.metaintro.com/jobs/nurse/locations/columbia-sc"
language: "en"
author: "Metaintro"
data_as_of: "2026-11-04T04:30:12.144Z"
cite_as: "Metaintro job-market data. https://www.metaintro.com/jobs/nurse/locations/columbia-sc"
data: ["https://www.metaintro.com/jobs/nurse/locations/columbia-sc/data.json"]
---

Nurse market brief · Columbia, SC

# Nurse Jobs in Columbia, SC

1,360 nurse openings are live in the Columbia, SC area from 105 employers, led by PrismaHealth, Lexington Medical Center, and MUSC. The middle half of posted salaries runs $91,546–$116,064 a year (median $102,492), from the 52% of listings that disclose pay.

Data updated Nov 4, 2026

[Search live jobs](/jobs/search?q=Nurse+jobs+in+Columbia%2C+SC)[Browse all Nurse markets](/jobs/nurse)

## Role and market snapshot

A quick read on demand before you open the live listings

**Tracked jobs**
: 1,360
: Live nurse openings currently tracked in the Columbia market.

**Companies hiring**
: 105
: Distinct employers represented in this publishable market view.

**Median compensation**
: $102,492
: 52% of listings provide usable compensation data.

## Market analysis

Role-specific demand, level, employer, and compensation signals for this local market

Start with the level mix, then compare current demand, compensation coverage, and employer concentration before opening the live listings.

Level mix

### Career ladder

[Entry-level](/jobs/nurse/locations/columbia-sc/entry-level)742 jobs

[Mid-level](/jobs/nurse/locations/columbia-sc/mid-level)6 jobs

Level coverage is 55%. Counts remain visible, but fit guidance stays withheld until at least 60% of listings have a reliable level signal.

30-day window

### Demand and salary

Current jobs

1,360

Hiring employers

105

Salary coverage

52%

Median experience

1.0 years

Within this market

### Employer tier lens

Startups & growing teams

734

56 companies · $101,348 median

Established employers

319

24 companies · $107,229 median

Top of market

102

14 companies

Coverage-gated

### Salary distribution

P25

$91,546

P50

$102,492

P75

$116,064

P90

$135,096

Salary figures use annualized USD posted minimum compensation from listings in this market. An employer that posts the same pay on many listings counts once, and figures render only when enough distinct employers disclose pay.

Use Metaintro

### Turn this market signal into momentum

Move from aggregate demand to the live roles hiring in this market now.

- Open live nurse listings in Columbia
- Compare the level mix before narrowing your search
- Use employer and compensation signals to prioritize outreach

[Search live jobs](/jobs/search?q=Nurse+jobs+in+Columbia%2C+SC)[Get started free](/signup)

## Turn this market brief into a live search.

Use the signal

The best next step is opening the roles behind the aggregate: compare nurse opportunities in Columbia, save the strongest fits, and keep the market signal close while you apply.

- 1,360 live roles tracked in this market.
- 105 employers represented in the current window.
- Market data refreshed Nov 4, 2026.

[Search live jobs](/jobs/search?q=Nurse+jobs+in+Columbia%2C+SC)[Compare other markets](/jobs/nurse)

## A practical market plan for Nurse in Columbia

Use this sequence to move from aggregate labor-market data to a focused application list.

1. 01Read the demand 1,360 nurse openings across 105 employers establish the current Columbia opportunity set.
2. 02Choose the right rung Use the live listings to calibrate title, scope, and experience expectations before applying.
3. 03Prioritize employers PrismaHealth is one of the most active visible employers, with 121 current openings in this market view.
4. 04Open the live roles 24 representative openings connect this brief to jobs you can review now.

With Metaintro

Keep market research, live opportunities, saved roles, and the evidence behind your applications moving in one focused loop.

## Where this market is hiring

Move from the Columbia market view into active employers and representative nurse openings

Employer activity · 105 companies

### Who is hiring in this market

The most active visible employers, ordered by openings represented in the current market sample.

[![PrismaHealth logo](/api/company-logo?url=https%3A%2F%2Fprismahealth.org%2Fapple-touch-icon.png&sig=CrTyHCNcMqodqIZlHQuIcvbb3WasH3yIJkIc_l_VmIk) PrismaHealthEstablished employers121Open roles](/company/prismahealth)![Lexington Medical Center logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.google.com%2Fs2%2Ffavicons%3Fdomain%3Dlexingtonmedicalcenter.com%26sz%3D128)
Lexington Medical CenterEmployer profile115Open roles
[![MUSC logo](/api/company-logo?url=https%3A%2F%2Fd3crna64wemw02.cloudfront.net%2Fasset%2F339713052848%2Fimage_mm92lu8uqd1pl64qa937agao1n%2F%3Fcontent-disposition%3Dinline&sig=_Ppad97Sg8J2ZU82krF9CiJg0lqlAIcbhILT4KgPnlA) MUSCStartups & growing teams112Open roles](/company/musc)
LiquidAgents HealthcareStartups & growing teams60Open roles
[![IMCS Group logo](/api/company-logo?url=https%3A%2F%2Fimcs-group.com%2Fwp-content%2Fthemes%2Fimcs%2Ffavicons%2Fapple-touch-icon.png&sig=6odM9_QGQFc-fh4cpMICoxJW7QAl1CdMsFSyMTlMfL0) IMCS GroupTop of market43Open roles](/company/imcs-d8ace529)
Infojini Inc.Startups & growing teams41Open roles
[![StaffDNA logo](/api/company-logo?url=https%3A%2F%2Fstaffdna.com%2Fwp-content%2Fuploads%2F2025%2F09%2Fsdna-mark-1024sqt-300x300.png&sig=vY5N2RzVohDGeOposMGEuZmdiuLWLq5R-q5QPH4TC6Q) StaffDNAStartups & growing teams40Open roles](/company/staffdna)[![Convergence Medical Staffing logo](/api/company-logo?url=https%3A%2F%2Fcmstaff.com%2Fwp-content%2Fuploads%2F2020%2F08%2Fcropped-icon_CMStaff-Site-Identity-240x240.png&sig=EqRn3ImLbYKwk3IYfxo0_CUNVFJKOL_99U88BxXOt3s) Convergence Medical StaffingEstablished employers37Open roles](/company/convergence-medical-staffing)

Live opportunity sample · 24 of 1,360 matches

### Representative openings

Open a role to inspect the full requirements. Compensation appears only when the listing provides usable salary data.

[Registered Nurse (RN) - Acute Care, Facility Resource Pool, PT, NightsEntry-levelPrisma Health-UpstateColumbia, South CarolinaPosted Nov 3, 2026](/job/registered-nurse-rn-acute-care-facility-resource-pool-pt-nights-at-5d81387a-8118-5475-9214-741e5888ff1f)[RN - Intermediate ICU (IICU)Entry-levelLexington Medical CenterWest Columbia, South CarolinaPosted Nov 3, 2026](/job/rn-intermediate-icu-iicu-at-lexington-medical-center-996dd823-b311-5aa9-aefc-e94800dbb6c4)[RN-LTAC, TravelLive roleLiquidAgents HealthcareColumbia, South Carolina$138,759Posted Nov 3, 2026](/job/rn-ltac-travel-at-liquidagents-healthcare-edb737f7-bf47-501c-8e1d-c09307d0b1ab)[Registered Nurse (RN) - Acute Care, Neurosurgical ICU, FT, NightsEntry-levelPrismaHealthColumbia, South CarolinaPosted Nov 2, 2026](/job/registered-nurse-rn-acute-care-neurosurgical-icu-ft-nights-at-aefa5402-9afa-5a79-82d9-a8fde0a0e3e7)[Outcomes Coordinator RN - Regulatory Readiness/Patient SafetyMid-levelLexington Medical CenterWest Columbia, South CarolinaPosted Nov 2, 2026](/job/outcomes-coordinator-rn-regulatory-readiness-patient-safety-at-3fb6d425-ca57-54b3-b8e9-3a37b4cc512b)[RN-ER, TravelEntry-levelCuready Healthcare StaffingColumbia, South Carolina$114,660Posted Nov 2, 2026](/job/rn-er-travel-at-cuready-healthcare-staffing-0f19e2a1-efc3-5a93-bde2-f57c832fe1ee)[RN-ER, TravelEntry-levelCuready Healthcare StaffingColumbia, South Carolina$114,660Posted Nov 2, 2026](/job/rn-er-travel-at-cuready-healthcare-staffing-09f7e43a-9990-5f90-810d-a94e2a94339b)[Registered Nurse (RN) - Acute Care, Neurosurgical ICU, FT, NightsEntry-levelPrisma Health-UpstateColumbia, South CarolinaPosted Nov 2, 2026](/job/registered-nurse-rn-acute-care-neurosurgical-icu-ft-nights-at-prisma-a1d22429-8fc6-5a6b-ba36-bf9edcc535db)
#### More nurse openings in Columbia

- [Registered Nurse (RN) - Acute Care, Facility Resource Pool, PT, Days · Prisma Health-Upstate](/job/registered-nurse-rn-acute-care-facility-resource-pool-pt-days-at-6154d214-f329-5f37-9323-b387e0609ac9)
- [RN-PCU/IMC, Travel · Skyline Med Staff](/job/rn-pcu-imc-travel-at-skyline-med-staff-1907265b-189e-5038-a443-8af46bc2b099)
- [Registered Nurse (RN) - Acute Care, Facility Resource Pool, PT, Days · PrismaHealth](/job/registered-nurse-rn-acute-care-facility-resource-pool-pt-days-at-a7908d70-a06a-526c-818e-3e4bac0ec724)
- [Registered Nurse II - Dialysis- PRN · MUSC](/job/registered-nurse-ii-dialysis-prn-at-musc-4a4242ca-4a55-5e74-96c3-ffac1bb8c950)
- [PCU RN · Grace Federal Solutions](/job/pcu-rn-at-grace-federal-solutions-932cc21a-62fe-53de-9d19-9a623a02aa1c)
- [Registered Nurse (RN) - Acute Care, Facility Resource Pool, PT, Days · PrismaHealth](/job/registered-nurse-rn-acute-care-facility-resource-pool-pt-days-at-17c812ef-9447-51ec-adff-9a66a5bdd5fa)
- [Registered Nurse RN · Seven Oaks Rehabilitation and Healthcare Center](/job/registered-nurse-rn-at-seven-oaks-rehabilitation-and-healthcare-center-f7b5695a-73ef-5c86-a674-d2624121157f)
- [Clinical Review Nurse - Concurrent Review - J00933 · A-Line Staffing Solutions](/job/clinical-review-nurse-concurrent-review-j00933-at-a-line-staffing-f0b78f53-4157-5d67-9e6f-0c43aa02847e)
- [RN - TELE · Accurate Staffing child board (JobRobotix)](/job/rn-tele-at-accurate-staffing-child-board-jobrobotix-929a9a16-ccd8-5afa-ab19-624971019bed)
- [STEP RN · Accurate Staffing - child board (Symplr)](/job/step-rn-at-accurate-staffing-child-board-symplr-8187b6d1-3692-5871-acf2-707340abf76f)
- [RN - TELE · Accurate Staffing child board (JobRobotix)](/job/rn-tele-at-accurate-staffing-child-board-jobrobotix-49fe90f2-f586-5bc5-b460-ea210a7e54f9)
- [RN - STEP · Accurate Staffing child board (JobRobotix)](/job/rn-step-at-accurate-staffing-child-board-jobrobotix-725d5549-db81-5b95-aec4-cb1793f5fca6)
- [Stepdown RN · Plexsum Staffing Solutions, Inc.](/job/stepdown-rn-at-plexsum-staffing-solutions-inc-c99f2eb5-9e46-517c-aaf2-7ad27ed0625f)
- [RN - PACU · Accurate Staffing child board (JobRobotix)](/job/rn-pacu-at-accurate-staffing-child-board-jobrobotix-ef8dcf03-046c-5716-a7ad-7a5d71f9040e)
- [Registered Nurse (RN)-Ambulatory, OBGYN, FT, Day · Prisma Health-Upstate](/job/registered-nurse-rn-ambulatory-obgyn-ft-day-at-prisma-health-upstate-a6ae99da-0871-5c37-9fbd-f02d3dfed751)
- [Registered Nurse RN Home Health · Enhabit Home Health & Hospice](/job/registered-nurse-rn-home-health-at-enhabit-home-health-and-hospice-fd011f11-8100-57fb-9c45-df227cecb8e7)

[Explore all 1,360 matching jobs](/jobs/search?q=Nurse+jobs+in+Columbia%2C+SC)

## Nurse jobs in Columbia: what applicants need to know

Current answers for a difficult AI-era job search, grounded in this publishable role and location market view rather than generic career advice.

1. 01### How many nurse jobs are open in Columbia? Metaintro tracks 1,360 live nurse openings from 105 employers in the Columbia, SC area over the last 30 days.
2. 02### What do nurse jobs in Columbia pay? The median posted salary is $102,492 a year. The middle half of posted salaries runs $91,546 to $116,064. Based on the 52% of current listings that disclose pay.
3. 03### Which companies are hiring for nurse jobs in Columbia? PrismaHealth, Lexington Medical Center, MUSC, and LiquidAgents Healthcare have the most open nurse roles here right now, out of 105 hiring employers.

## Continue with the next market signal

Compare nearby cities, adjacent roles, and publishable level views without leaving the live jobs cluster

Nearby cities

Compare Nurse demand around Columbia.

[Charlotte, NC](/jobs/nurse/locations/charlotte-nc)[Charleston, SC](/jobs/nurse/locations/charleston-sc)[Savannah, GA](/jobs/nurse/locations/savannah-ga)[Athens, GA](/jobs/nurse/locations/athens-ga)[Asheville, NC](/jobs/nurse/locations/asheville-nc)[Fayetteville, NC](/jobs/nurse/locations/fayetteville-nc)

Related roles

See adjacent role demand in the Columbia market.

[Medical Assistant](/jobs/medical-assistant/locations/columbia-sc)[Certified Nursing Assistant](/jobs/certified-nursing-assistant/locations/columbia-sc)[Nurse Practitioner](/jobs/nurse-practitioner/locations/columbia-sc)[All roles in Columbia](/jobs/locations/columbia-sc)

Level views

Narrow the market to experience levels with enough reliable data.

[Entry-level Nurse](/jobs/nurse/locations/columbia-sc/entry-level)[Mid-level Nurse](/jobs/nurse/locations/columbia-sc/mid-level)

Built for career movement

## Turn the Columbia nurse market into your next move.

Use live demand, employer, level, and compensation signals to focus your nurse search where the market is active now.

[Search live jobs](/jobs/search?q=Nurse+jobs+in+Columbia%2C+SC)[Get started free](/signup)

- MatchCompare live roles against your current evidence.
- PositionTurn proof projects into role-specific applications.
- ImproveUse market feedback to keep the skill plan current.

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