--- title: "Physician Assistant Jobs in Columbia, SC | Metaintro" canonical: "https://www.metaintro.com/jobs/physician-assistant/locations/columbia-sc" language: "en" author: "Metaintro" data_as_of: "2026-11-04T04:30:12.144Z" cite_as: "Metaintro job-market data. https://www.metaintro.com/jobs/physician-assistant/locations/columbia-sc" data: ["https://www.metaintro.com/jobs/physician-assistant/locations/columbia-sc/data.json"] --- Physician Assistant market brief · Columbia, SC # Physician Assistant Jobs in Columbia, SC 74 physician assistant openings are live in the Columbia, SC area from 10 employers, led by PrismaHealth, Lexington Medical Center, and Prisma Health UC by Wellstreet, LLC. Data updated Nov 4, 2026 [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Columbia%2C+SC)[Browse all Physician Assistant markets](/jobs/physician-assistant) ## Role and market snapshot A quick read on demand before you open the live listings **Tracked jobs** : 74 : Live physician assistant openings currently tracked in the Columbia market. **Companies hiring** : 10 : Distinct employers represented in this publishable market view. **Median compensation** : Not published : Not enough employers here disclose pay to publish a local median, so none is shown. ## Market analysis Role-specific demand, level, employer, and compensation signals for this local market Start with the level mix, then compare current demand, compensation coverage, and employer concentration before opening the live listings. Level mix ### Career ladder [Entry-level](/jobs/physician-assistant/locations/columbia-sc/entry-level)35 jobs Level coverage is 47%. Counts remain visible, but fit guidance stays withheld until at least 60% of listings have a reliable level signal. 30-day window ### Demand and salary Current jobs 74 Hiring employers 10 Salary coverage 3% Median experience 0.0 years Use Metaintro ### Turn this market signal into momentum Move from aggregate demand to the live roles hiring in this market now. - Open live physician assistant listings in Columbia - Compare the level mix before narrowing your search - Use employer and compensation signals to prioritize outreach [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Columbia%2C+SC)[Get started free](/signup) ## Turn this market brief into a live search. Use the signal The best next step is opening the roles behind the aggregate: compare physician assistant opportunities in Columbia, save the strongest fits, and keep the market signal close while you apply. - 74 live roles tracked in this market. - 10 employers represented in the current window. - Market data refreshed Nov 4, 2026. [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Columbia%2C+SC)[Compare other markets](/jobs/physician-assistant) ## A practical market plan for Physician Assistant in Columbia Use this sequence to move from aggregate labor-market data to a focused application list. 1. 01Read the demand 74 physician assistant openings across 10 employers establish the current Columbia opportunity set. 2. 02Choose the right rung Use the live listings to calibrate title, scope, and experience expectations before applying. 3. 03Prioritize employers PrismaHealth is one of the most active visible employers, with 49 current openings in this market view. 4. 04Open the live roles 24 representative openings connect this brief to jobs you can review now. With Metaintro Keep market research, live opportunities, saved roles, and the evidence behind your applications moving in one focused loop. ## Where this market is hiring Move from the Columbia market view into active employers and representative physician assistant openings Employer activity · 10 companies ### Who is hiring in this market The most active visible employers, ordered by openings represented in the current market sample. [![PrismaHealth logo](/api/company-logo?url=https%3A%2F%2Fprismahealth.org%2Fapple-touch-icon.png&sig=CrTyHCNcMqodqIZlHQuIcvbb3WasH3yIJkIc_l_VmIk) PrismaHealthStartups & growing teams49Open roles](/company/prismahealth)![Lexington Medical Center logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.google.com%2Fs2%2Ffavicons%3Fdomain%3Dlexingtonmedicalcenter.com%26sz%3D128) Lexington Medical CenterEmployer profile7Open roles Prisma Health UC by Wellstreet, LLCEmployer profile5Open roles Prisma Health-UpstateEmployer profile5Open roles WEL1014WELSEmployer profile3Open roles [![Arthritis Knee Pain Centers logo](/api/company-logo?url=https%3A%2F%2Farthritiskneepain.com%2Fjjwp%2Fwp-content%2Fuploads%2F2024%2F02%2Fcropped-akpc-logo-180x180.png&sig=phRiIXwM5g-PezldJbqOhNSAUhFDBCnAp8mbdovHOXc) Arthritis Knee Pain CentersTop of market1Open roles](/company/arthritis-knee-pain-centers)[![Commonwealth Medical Services logo](/api/company-logo?url=https%3A%2F%2Fcmslexington.com%2Fwp-content%2Fuploads%2F2021%2F11%2FCommonwealth-Medical-Services-Lexington-Kentucky.png&sig=rkSzXyvfsuMPtck0UgJoiNXF3Uf8AkHnnP5EBSXicmU) Commonwealth Medical ServicesTop of market1Open roles](/company/commonwealth-medical-services) Kidzcare PediatricsEmployer profile1Open roles Live opportunity sample · 24 of 74 matches ### Representative openings Open a role to inspect the full requirements. Compensation appears only when the listing provides usable salary data. [Physician Assistant - Pain MedicineLive rolePhysician Assistant SolutionsColumbia, South Carolina$120,000Posted Nov 1, 2026](/job/physician-assistant-pain-medicine-at-physician-assistant-solutions-06e5f739-c5b1-5a26-9dc5-edfab3afdabd)[Physician Assistant - LHHVC / Vascular SurgeryEntry-levelLexington Medical CenterWest Columbia, South CarolinaPosted Oct 30, 2026](/job/physician-assistant-lhhvc-vascular-surgery-at-lexington-medical-center-eed38e8a-1ecb-5213-b7ed-ae76699ef8fa)[Nurse Practitioner / Physician Assistant - Pulmonology - ColumbiaLive rolePrismaHealthColumbia, South CarolinaPosted Oct 21, 2026](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-02c96bd4-a49d-5eb9-8be8-d4e4fd798875)[Nurse Practitioner / Physician Assistant - Pulmonology - ColumbiaLive rolePrismaHealthColumbia, South CarolinaPosted Oct 21, 2026](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-104b0cbe-add4-5904-bc57-cca06e48fb19)[Nurse Practitioner / Physician Assistant - Pulmonology - ColumbiaLive rolePrismaHealthColumbia, South CarolinaPosted Oct 21, 2026](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-a8d082e9-5024-5d49-8d53-785404e90de7)[Nurse Practitioner / Physician Assistant - Pulmonology - ColumbiaLive rolePrisma Health-UpstateColumbia, South CarolinaPosted Oct 21, 2026](/job/nurse-practitioner-physician-assistant-pulmonology-columbia-at-prisma-244d1a32-a79e-5881-8761-d8fa1d958a7f)[Nurse Practitioner or Physician Assistant- Primary Care - Optum/Colonial HealthcareLive roleUnitedHealth GroupColumbia, South Carolina$104,500Posted Oct 21, 2026](/job/nurse-practitioner-or-physician-assistant-primary-care-optum-colonial-350221f1-7a8c-5296-b1e6-8755ac471ccc)[Urgent Care Nurse Practitioner or Physician Assistant- Columbia, SC (Float)Live roleWEL1014WELSColumbia, South CarolinaPosted Oct 15, 2026](/job/urgent-care-nurse-practitioner-or-physician-assistant-columbia-sc-546b27b4-2ed7-516f-a970-b58645dab256) #### More physician assistant openings in Columbia - [Urgent Care Nurse Practitioner or Physician Assistant- Columbia, SC (Float) · Prisma Health UC by Wellstreet, LLC](/job/urgent-care-nurse-practitioner-or-physician-assistant-columbia-sc-c904f246-7eb4-560e-8510-b65668ce06a9) - [Nurse Practitioner / Physician Assistant - Urology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-urology-columbia-at-dab3b272-d54a-5c5c-86ef-733c554a115b) - [Nurse Practitioner / Physician Assistant - Urology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-urology-columbia-at-11f94dce-0d70-5502-9c4d-f541954e6f1a) - [Nurse Practitioner / Physician Assistant - Urology - Columbia · Prisma Health-Upstate](/job/nurse-practitioner-physician-assistant-urology-columbia-at-prisma-45e5ffd2-4405-50ad-82eb-ee0a383f9909) - [Nurse Practitioner / Physician Assistant - Urology - Columbia · PrismaHealth](/job/nurse-practitioner-physician-assistant-urology-columbia-at-751348b7-5b18-56ed-a473-d471cc0de6f2) - [Physician Assistant - Lexington Brain & Spine Institute · Lexington Medical Center](/job/physician-assistant-lexington-brain-and-spine-institute-at-lexington-2dcf2349-5d2a-5c04-91bf-d27c3fbe3afe) - [Radiation Oncology: Nurse Practitioner/Physician Assistant (Columbia) · PrismaHealth](/job/radiation-oncology-nurse-practitioner-physician-assistant-columbia-at-80fbd658-285f-5d7c-a624-bbd5721943de) - [Radiation Oncology: Nurse Practitioner/Physician Assistant (Columbia) · PrismaHealth](/job/radiation-oncology-nurse-practitioner-physician-assistant-columbia-at-51fce4eb-f588-5616-85f4-e37cf36dfbbd) - [Radiation Oncology: Nurse Practitioner/Physician Assistant (Columbia) · PrismaHealth](/job/radiation-oncology-nurse-practitioner-physician-assistant-columbia-at-c8eb5817-9e5b-5143-80c8-478b66d9f903) - [Advanced Practice Provider (Nurse Practitioner or Physician Assistant) · Kidzcare Pediatrics](/job/advanced-practice-provider-nurse-practitioner-or-physician-assistant-b1289cfd-a1de-5aae-bd8c-adfa098c4759) - [Radiation Oncology: Nurse Practitioner/Physician Assistant (Columbia) · Prisma Health-Upstate](/job/radiation-oncology-nurse-practitioner-physician-assistant-columbia-at-63ade2dd-fd4d-5697-8671-8c7d7394163f) - [Physician Assistant - Ortho-Spine - Columbia · Prisma Health-Upstate](/job/physician-assistant-ortho-spine-columbia-at-prisma-health-upstate-ec9b4ec4-607c-5386-af1a-2b1c64fbf13a) - [Physician Assistant - Ortho-Spine - Columbia · PrismaHealth](/job/physician-assistant-ortho-spine-columbia-at-prismahealth-ce0c9724-6827-562e-9273-13e64964da4b) - [Physician Assistant - Ortho-Spine - Columbia · PrismaHealth](/job/physician-assistant-ortho-spine-columbia-at-prismahealth-11e15cd4-bc72-5ec0-8dbb-b2d490e33204) - [Physician Assistant - Ortho-Spine - Columbia · PrismaHealth](/job/physician-assistant-ortho-spine-columbia-at-prismahealth-8ebcba68-0437-5ed8-a8ee-114895afc977) - [Physician Assistant · Lexington Medical Center](/job/physician-assistant-at-lexington-medical-center-c69a9839-d423-5802-ba71-43df44011c58) [Explore all 74 matching jobs](/jobs/search?q=Physician+Assistant+jobs+in+Columbia%2C+SC) ## Physician Assistant jobs in Columbia: what applicants need to know Current answers for a difficult AI-era job search, grounded in this publishable role and location market view rather than generic career advice. 1. 01### How many physician assistant jobs are open in Columbia? Metaintro tracks 74 live physician assistant openings from 10 employers in the Columbia, SC area over the last 30 days. 2. 02### Which companies are hiring for physician assistant jobs in Columbia? PrismaHealth, Lexington Medical Center, Prisma Health UC by Wellstreet, LLC, and Prisma Health-Upstate have the most open physician assistant roles here right now, out of 10 hiring employers. ## Continue with the next market signal Compare nearby cities, adjacent roles, and publishable level views without leaving the live jobs cluster Nearby cities Compare Physician Assistant demand around Columbia. [Charlotte, NC](/jobs/physician-assistant/locations/charlotte-nc)[Charleston, SC](/jobs/physician-assistant/locations/charleston-sc)[Savannah, GA](/jobs/physician-assistant/locations/savannah-ga)[Athens, GA](/jobs/physician-assistant/locations/athens-ga)[Asheville, NC](/jobs/physician-assistant/locations/asheville-nc)[Fayetteville, NC](/jobs/physician-assistant/locations/fayetteville-nc) Related roles See adjacent role demand in the Columbia market. [Nurse Practitioner](/jobs/nurse-practitioner/locations/columbia-sc)[Nurse](/jobs/nurse/locations/columbia-sc)[All roles in Columbia](/jobs/locations/columbia-sc) Level views Narrow the market to experience levels with enough reliable data. [Entry-level Physician Assistant](/jobs/physician-assistant/locations/columbia-sc/entry-level) Built for career movement ## Turn the Columbia physician assistant market into your next move. Use live demand, employer, level, and compensation signals to focus your physician assistant search where the market is active now. [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Columbia%2C+SC)[Get started free](/signup) - MatchCompare live roles against your current evidence. - PositionTurn proof projects into role-specific applications. - ImproveUse market feedback to keep the skill plan current. [Return to navigation](#main-navigation)