---
title: "Physician Assistant Jobs in Durham, NC | Metaintro"
canonical: "https://www.metaintro.com/jobs/physician-assistant/locations/durham-nc"
language: "en"
author: "Metaintro"
data_as_of: "2026-11-05T04:10:12.216Z"
cite_as: "Metaintro job-market data. https://www.metaintro.com/jobs/physician-assistant/locations/durham-nc"
data: ["https://www.metaintro.com/jobs/physician-assistant/locations/durham-nc/data.json"]
---

Physician Assistant market brief · Durham, NC

# Physician Assistant Jobs in Durham, NC

88 physician assistant openings are live in the Durham, NC area from 13 employers, led by Duke Health, Duke Careers, and MainStreet Family Care.

Data updated Nov 5, 2026

[Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Durham%2C+NC)[Browse all Physician Assistant markets](/jobs/physician-assistant)

## Role and market snapshot

A quick read on demand before you open the live listings

**Tracked jobs**
: 88
: Live physician assistant openings currently tracked in the Durham market.

**Companies hiring**
: 13
: Distinct employers represented in this publishable market view.

**Median compensation**
: Not published
: Not enough employers here disclose pay to publish a local median, so none is shown.

## Market analysis

Role-specific demand, level, employer, and compensation signals for this local market

Start with the level mix, then compare current demand, compensation coverage, and employer concentration before opening the live listings.

Level mix

### Career ladder

[Entry-level](/jobs/physician-assistant/locations/durham-nc/entry-level)25 jobs

Level coverage is 28%. Counts remain visible, but fit guidance stays withheld until at least 60% of listings have a reliable level signal.

30-day window

### Demand and salary

Current jobs

88

Hiring employers

13

Salary coverage

6%

Median experience

1.0 years

Within this market

### Employer tier lens

Startups & growing teams

51

5 companies

Established employers

20

4 companies

Use Metaintro

### Turn this market signal into momentum

Move from aggregate demand to the live roles hiring in this market now.

- Open live physician assistant listings in Durham
- Compare the level mix before narrowing your search
- Use employer and compensation signals to prioritize outreach

[Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Durham%2C+NC)[Get started free](/signup)

## Turn this market brief into a live search.

Use the signal

The best next step is opening the roles behind the aggregate: compare physician assistant opportunities in Durham, save the strongest fits, and keep the market signal close while you apply.

- 88 live roles tracked in this market.
- 13 employers represented in the current window.
- Market data refreshed Nov 5, 2026.

[Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Durham%2C+NC)[Compare other markets](/jobs/physician-assistant)

## A practical market plan for Physician Assistant in Durham

Use this sequence to move from aggregate labor-market data to a focused application list.

1. 01Read the demand 88 physician assistant openings across 13 employers establish the current Durham opportunity set.
2. 02Choose the right rung Use the live listings to calibrate title, scope, and experience expectations before applying.
3. 03Prioritize employers Duke Health is one of the most active visible employers, with 41 current openings in this market view.
4. 04Open the live roles 24 representative openings connect this brief to jobs you can review now.

With Metaintro

Keep market research, live opportunities, saved roles, and the evidence behind your applications moving in one focused loop.

## Where this market is hiring

Move from the Durham market view into active employers and representative physician assistant openings

Employer activity · 13 companies

### Who is hiring in this market

The most active visible employers, ordered by openings represented in the current market sample.

[![Duke Health logo](/api/company-logo?url=https%3A%2F%2Fwww.dukehealth.org%2Fthemes%2Fcustom%2Fdukehealth%2Fimages%2Fapple-touch-icon-152x152-precomposed.png&sig=Cvk2iUJQt8ZT2sjs29VOqGutlp7HvGJyoykQIKFQ1ck) Duke HealthStartups & growing teams41Open roles](/company/duke-health)
Duke CareersEmployer profile13Open roles
[![MainStreet Family Care logo](/api/company-logo?url=https%3A%2F%2Fwww.mainstreetfamilycare.com%2Fwp-content%2Fuploads%2F2022%2F06%2Fcropped-favicon-180x180.png&sig=iWvcirgOUYhxtvK1Fg4GPBW1AhHN7HOOzfD0jTs2OgQ) MainStreet Family CareEstablished employers13Open roles](/company/mainstreet-family-care)[![EMrecruits logo](/api/company-logo?url=https%3A%2F%2Fwww.emrecruits.com%2Fhs-fs%2Ffile-402192547-png%2Ffavicons%2Fapple-icon-144x144-precomposed.png&sig=PAhDnViUdWvzdGveEU1lsp1eGMzfSTshA53WQYuZigw) EMrecruitsStartups & growing teams6Open roles](/company/emrecruits)[![Premise Health logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.premisehealth.com%2Ffavicon.ico) Premise HealthEstablished employers4Open roles](/company/premise-health)[![Avance Care logo](/api/company-logo?url=https%3A%2F%2Fwww.avancecare.com%2Fwp-content%2Fuploads%2F2021%2F11%2Fcropped-cropped-favicon-500x500.png&sig=BdENfViqG7jVV91j6Kevm26Ui_t7uHP32QlVTT4UWak) Avance CareEstablished employers2Open roles](/company/avance-care)[![Curana Health logo](/api/company-logo?url=https%3A%2F%2Fcuranahealth.com%2Fwp-content%2Fuploads%2F2025%2F10%2Fcropped-Curana-Health-Favicon-180x180.webp&sig=WZYi8Rz1N5fTH17DhOoVJDV78OjRPfoiXRn6R1vmcKo) Curana HealthTop of market2Open roles](/company/curana-health)
TinkBird Healthcare StaffingStartups & growing teams2Open roles

Live opportunity sample · 24 of 88 matches

### Representative openings

Open a role to inspect the full requirements. Compensation appears only when the listing provides usable salary data.

[Nurse Practitioner or Physician Assistant- Medical OncologyLive roleDuke HealthDurham, North CarolinaPosted Nov 3, 2026](/job/nurse-practitioner-or-physician-assistant-medical-oncology-at-duke-b1aabece-493c-502c-a4e8-c0d8cfdd0887)[Nurse Practitioner or Physician Assistant - Hematologic Malignancy and Cellular Therapy (HMCT)Live roleDuke HealthDurham, North CarolinaPosted Nov 3, 2026](/job/nurse-practitioner-or-physician-assistant-hematologic-malignancy-and-1113a81e-3593-5aa3-b562-b3c4a6026dd2)[Nurse Practitioner/Physician Assistant: Duke Orthopaedics Urgent CareEntry-levelDuke CareersGarner, North CarolinaPosted Nov 2, 2026](/job/nurse-practitioner-physician-assistant-duke-orthopaedics-urgent-care-e6004b5b-c220-5c3f-a1a3-3595a96b8555)[Nurse Practitioner/Physician Assistant: Duke Orthopaedics Urgent CareEntry-levelDuke HealthGarner, North CarolinaPosted Nov 2, 2026](/job/nurse-practitioner-physician-assistant-duke-orthopaedics-urgent-care-3cc6249c-1663-508d-aba7-8ddeb5dc9618)[Physician AssistantLive roleAvance CareClayton, North CarolinaPosted Oct 29, 2026](/job/physician-assistant-at-avance-care-8573395c-7059-583b-919d-e3c67428efb6)[PMHNP or Psychiatric Physician Assistant - OutpatientLive roleMonarchCary, North CarolinaPosted Oct 28, 2026](/job/pmhnp-or-psychiatric-physician-assistant-outpatient-at-monarch-e036c2cf-b8cc-53da-9b38-c84af279675f)[Physician Assistant - Anesthesiology/Pain ClinicEntry-levelVeterans Health AdministrationDurham, North Carolina$130,584Posted Oct 26, 2026](/job/physician-assistant-anesthesiology-pain-clinic-at-veterans-health-62396dda-9518-5141-9308-5c79cdf75c69)[Physician Assistant, Part-timeEntry-levelPremise HealthClayton, North CarolinaPosted Oct 23, 2026](/job/physician-assistant-part-time-at-premise-health-019d78f2-6219-542e-a6bc-244ec0cebd52)
#### More physician assistant openings in Durham

- [Physician Assistant/Nurse Practitioner - Duke Children's Health Center Nephrology · Duke Careers](/job/physician-assistant-nurse-practitioner-duke-childrens-health-center-11c92da0-8a30-5eeb-bfb4-1e1f64829d74)
- [Physician Assistant/Nurse Practitioner - Duke Children's Health Center Nephrology · Duke Health](/job/physician-assistant-nurse-practitioner-duke-childrens-health-center-6e0b2e52-6a40-58f5-8ac0-5a842bdc7d09)
- [Physician Assistant, Part-time · Premise Health](/job/physician-assistant-part-time-at-premise-health-1dfef9f6-aa21-5a22-b308-9315252309aa)
- [Nurse Practitioner or Physician Assistant - Nocturnist with Hospitalist Medicine · Duke Health](/job/nurse-practitioner-or-physician-assistant-nocturnist-with-hospitalist-4b93bd41-341f-5759-8948-bb20b544ce84)
- [Nurse Practitioner or Physician Assistant - Nocturnist with Hospitalist Medicine · Duke Careers](/job/nurse-practitioner-or-physician-assistant-nocturnist-with-hospitalist-826bcee6-ef59-5271-a4c0-740bd59dc3d6)
- [Nurse Practitioner/Physician Assistant - Abdominal Transplant Surgery - PRN · Duke Health](/job/nurse-practitioner-physician-assistant-abdominal-transplant-surgery-0aa233a5-ccbb-58d9-9e1e-febc601f1279)
- [Nurse Practitioner/Physician Assistant - Duke Headache Clinic · Duke Health](/job/nurse-practitioner-physician-assistant-duke-headache-clinic-at-duke-3a825077-a993-536a-8fa4-81874b334120)
- [Nurse Practitioner/Physician Assistant - Duke Headache Clinic · Duke Careers](/job/nurse-practitioner-physician-assistant-duke-headache-clinic-at-duke-a77bab6e-f739-5a3c-b5af-f5cdc830b9ad)
- [Floating Physician Assistant · MainStreet Family Care](/job/floating-physician-assistant-at-mainstreet-family-care-360c86aa-2c66-5cec-b3c3-ed7ea15fc1a2)
- [PRN Physician Assistant · MainStreet Family Care](/job/prn-physician-assistant-at-mainstreet-family-care-de4cc609-9943-5487-b152-56d4dfb6c345)
- [PRN Physician Assistant · MainStreet Family Care](/job/prn-physician-assistant-at-mainstreet-family-care-3e1f942c-3b23-5fed-b731-d5615501082f)
- [Clayton Physician Assistant · MainStreet Family Care](/job/clayton-physician-assistant-at-mainstreet-family-care-45ae3c3e-dff2-564e-b78a-39aafef9cf38)
- [Nurse Practitioner or Physician Assistant - Hematologic Malignancy and Cellular Therapy (HMCT) · Duke Health](/job/nurse-practitioner-or-physician-assistant-hematologic-malignancy-and-260cc8a1-c5d3-5faa-b0bc-9a4b93616ddb)
- [Physician Assistant – Urgent Care & Primary Care | Raleigh and Wake Forest, NC · EMrecruits](/job/physician-assistant-urgent-care-and-primary-care-raleigh-and-wake-d0820340-5a0a-527b-9e22-21e3f68f30a3)
- [Nurse Practitioner or Physician Assistant - Hematologic Malignancy and Cellular Therapy (HMCT) · Duke Careers](/job/nurse-practitioner-or-physician-assistant-hematologic-malignancy-and-80dcacb9-d1b9-54ad-8d69-00ce84417917)
- [Physician Assistant · MainStreet Family Care](/job/physician-assistant-at-mainstreet-family-care-888d8121-0b08-56e7-81f7-0e0f46a036a0)

[Explore all 88 matching jobs](/jobs/search?q=Physician+Assistant+jobs+in+Durham%2C+NC)

## Physician Assistant jobs in Durham: what applicants need to know

Current answers for a difficult AI-era job search, grounded in this publishable role and location market view rather than generic career advice.

1. 01### How many physician assistant jobs are open in Durham? Metaintro tracks 88 live physician assistant openings from 13 employers in the Durham, NC area over the last 30 days.
2. 02### Which companies are hiring for physician assistant jobs in Durham? Duke Health, Duke Careers, MainStreet Family Care, and EMrecruits have the most open physician assistant roles here right now, out of 13 hiring employers.

## Continue with the next market signal

Compare nearby cities, adjacent roles, and publishable level views without leaving the live jobs cluster

Nearby cities

Compare Physician Assistant demand around Durham.

[Raleigh, NC](/jobs/physician-assistant/locations/raleigh-nc)[Greensboro, NC](/jobs/physician-assistant/locations/greensboro-nc)[Fayetteville, NC](/jobs/physician-assistant/locations/fayetteville-nc)[Winston-Salem, NC](/jobs/physician-assistant/locations/winston-salem-nc)[Greenville, NC](/jobs/physician-assistant/locations/greenville-nc)[Lynchburg, VA](/jobs/physician-assistant/locations/lynchburg-va)

Related roles

See adjacent role demand in the Durham market.

[Nurse Practitioner](/jobs/nurse-practitioner/locations/durham-nc)[Nurse](/jobs/nurse/locations/durham-nc)[All roles in Durham](/jobs/locations/durham-nc)

Level views

Narrow the market to experience levels with enough reliable data.

[Entry-level Physician Assistant](/jobs/physician-assistant/locations/durham-nc/entry-level)

Built for career movement

## Turn the Durham physician assistant market into your next move.

Use live demand, employer, level, and compensation signals to focus your physician assistant search where the market is active now.

[Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Durham%2C+NC)[Get started free](/signup)

- MatchCompare live roles against your current evidence.
- PositionTurn proof projects into role-specific applications.
- ImproveUse market feedback to keep the skill plan current.

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