--- title: "Physician Assistant Jobs in Sioux Falls, SD | Metaintro" canonical: "https://www.metaintro.com/jobs/physician-assistant/locations/sioux-falls-sd" language: "en" author: "Metaintro" --- Physician Assistant market brief · Sioux Falls, SD # Physician Assistant Jobs in Sioux Falls, SD 16 physician assistant openings are live in the Sioux Falls, SD area from 4 employers, led by Sanford, Avera, and Lyra Health. 6% of listings accept remote work. Data updated Oct 11, 2026 [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Sioux+Falls%2C+SD)[Browse all Physician Assistant markets](/jobs/physician-assistant) ## Role and market snapshot A quick read on demand before you open the live listings **Tracked jobs** : 16 : Live physician assistant openings currently tracked in the Sioux Falls market. **Companies hiring** : 4 : Distinct employers represented in this publishable market view. **Median compensation** : Not published : Not enough employers here disclose pay to publish a local median, so none is shown. ## Market analysis Role-specific demand, level, employer, and compensation signals for this local market Start with the level mix, then compare current demand, compensation coverage, and employer concentration before opening the live listings. Level mix ### Career ladder Entry-level4 jobs Level coverage is 25%. Counts remain visible, but fit guidance stays withheld until at least 60% of listings have a reliable level signal. 30-day window ### Demand and salary Current jobs 16 Hiring employers 4 Salary coverage 0% Median experience 2.0 years Use Metaintro ### Turn this market signal into momentum Move from aggregate demand to the live roles hiring in this market now. - Open live physician assistant listings in Sioux Falls - Compare the level mix before narrowing your search - Use employer and compensation signals to prioritize outreach [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Sioux+Falls%2C+SD)[Get started free](/signup) ## Turn this market brief into a live search. Use the signal The best next step is opening the roles behind the aggregate: compare physician assistant opportunities in Sioux Falls, save the strongest fits, and keep the market signal close while you apply. - 16 live roles tracked in this market. - 4 employers represented in the current window. - Market data refreshed Oct 11, 2026. [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Sioux+Falls%2C+SD)[Compare other markets](/jobs/physician-assistant) ## A practical market plan for Physician Assistant in Sioux Falls Use this sequence to move from aggregate labor-market data to a focused application list. 1. 01Read the demand 16 physician assistant openings across 4 employers establish the current Sioux Falls opportunity set. 2. 02Choose the right rung Use the live listings to calibrate title, scope, and experience expectations before applying. 3. 03Prioritize employers Sanford is one of the most active visible employers, with 9 current openings in this market view. 4. 04Open the live roles 8 representative openings connect this brief to jobs you can review now. With Metaintro Keep market research, live opportunities, saved roles, and the evidence behind your applications moving in one focused loop. ## Where this market is hiring Move from the Sioux Falls market view into active employers and representative physician assistant openings Employer activity · 4 companies ### Who is hiring in this market The most active visible employers, ordered by openings represented in the current market sample. SanfordEmployer profile9Open roles [![Avera logo](/api/company-logo?url=https%3A%2F%2Feadn-wc04-17305433.nxedge.io%2Fwp-content%2Fuploads%2F2026%2F09%2Ffavicon-96x96-1.png&sig=TY_ZAfOh__AjYffCbMr1dKspsj7iWFMXda9zgpeuKBc) AveraTop of market3Open roles](/company/avera)[![Lyra Health logo](/api/company-logo?url=https%3A%2F%2Fwww.lyrahealth.com%2Fwp-content%2Fuploads%2F2026%2F02%2Fcropped-Favicon-180x180.png&sig=Dir03nzC8QOHFM22EDWySEi7V1zuLQ9UC_Jr6NIMUQ0) Lyra HealthStartups & growing teams3Open roles](/company/lyra-health)![Docs MSO LLC logo](/api/favicon-proxy?url=https%3A%2F%2Fwww.google.com%2Fs2%2Ffavicons%3Fdomain%3Ddocs.health%26sz%3D128) Docs MSO LLCEmployer profile1Open roles Live opportunity sample · 8 of 16 matches ### Representative openings Open a role to inspect the full requirements. Compensation appears only when the listing provides usable salary data. [APP - Nurse Practitioner or Physician Assistant | Inpatient Women'sLive roleSanfordSioux Falls, South DakotaPosted Sep 30, 2026](/job/app-nurse-practitioner-or-physician-assistant-inpatient-womens-at-dcab0fa7-d252-5f2d-8568-c357f6cda81e)[Nurse Practitioner or Physician Assistant | Urgent CareLive roleAveraSioux Falls, South DakotaPosted Sep 29, 2026](/job/nurse-practitioner-or-physician-assistant-urgent-care-at-avera-1bedd842-f08e-5515-9659-284260920f9b)[APP - Nurse Practitioner or Physician Assistant | NeurologyLive roleSanfordSioux Falls, South DakotaPosted Sep 28, 2026](/job/app-nurse-practitioner-or-physician-assistant-neurology-at-sanford-4e7886ca-2d78-571b-9d35-8a67bc9a9b43)[Nurse Practitioner or Physician Assistant | Neurology | InpatientLive roleAveraSioux Falls, South DakotaPosted Sep 24, 2026](/job/nurse-practitioner-or-physician-assistant-neurology-inpatient-at-avera-5f76a98a-459d-58ea-9c01-fac6078928f4)[APP - Nurse Practitioner or Physician Assistant | Cardiothoracic SurgeryLive roleSanfordSioux Falls, South DakotaPosted Sep 21, 2026](/job/app-nurse-practitioner-or-physician-assistant-cardiothoracic-surgery-9a4aa0b8-b3df-53f0-947b-1541d9b6f002)[APP - Nurse Practitioner or Physician Assistant | Pediatric Child AbuseLive roleSanfordSioux Falls, South DakotaPosted Sep 16, 2026](/job/app-nurse-practitioner-or-physician-assistant-pediatric-child-abuse-172bedd2-9dde-54ec-bcde-725325afe6b1)[APP - Nurse Practitioner or Physician Assistant | General SurgeryEntry-levelSanfordSioux Falls, South DakotaPosted Sep 11, 2026](/job/app-nurse-practitioner-or-physician-assistant-general-surgery-at-c92a6dd5-2089-5f45-ae74-c5d5381935f7)[APP - Nurse Practitioner or Physician Assistant | Gynecology OncologyLive roleSanfordSioux Falls, South DakotaPosted Sep 8, 2026](/job/app-nurse-practitioner-or-physician-assistant-gynecology-oncology-at-f11ed778-cd5d-5fe5-85f5-4dd56e6b1302) [Explore all 16 matching jobs](/jobs/search?q=Physician+Assistant+jobs+in+Sioux+Falls%2C+SD) ## Physician Assistant jobs in Sioux Falls: what applicants need to know Current answers for a difficult AI-era job search, grounded in this publishable role and location market view rather than generic career advice. 1. 01### How many physician assistant jobs are open in Sioux Falls? Metaintro tracks 16 live physician assistant openings from 4 employers in the Sioux Falls, SD area over the last 30 days. 2. 02### Which companies are hiring for physician assistant jobs in Sioux Falls? Sanford, Avera, Lyra Health, and Docs MSO LLC have the most open physician assistant roles here right now, out of 4 hiring employers. ## Continue with the next market signal Compare nearby cities, adjacent roles, and publishable level views without leaving the live jobs cluster Nearby cities Compare Physician Assistant demand around Sioux Falls. [Omaha, NE](/jobs/physician-assistant/locations/omaha-ne)[Lincoln, NE](/jobs/physician-assistant/locations/lincoln-ne)[Minneapolis, MN](/jobs/physician-assistant/locations/minneapolis-mn) Related roles See adjacent role demand in the Sioux Falls market. [Nurse Practitioner](/jobs/nurse-practitioner/locations/sioux-falls-sd)[Nurse](/jobs/nurse/locations/sioux-falls-sd)[All roles in Sioux Falls](/jobs/locations/sioux-falls-sd) Level views Narrow the market to experience levels with enough reliable data. More markets appear here after they clear Metaintro's data gate. ![](https://cdn.metaintro.com/rs:fill:1200:800/q:30/plain/images/bridges/bridge-expand.1df895c6bd76d96f.png) Built for career movement ## Turn the Sioux Falls physician assistant market into your next move. Use live demand, employer, level, and compensation signals to focus your physician assistant search where the market is active now. [Search live jobs](/jobs/search?q=Physician+Assistant+jobs+in+Sioux+Falls%2C+SD)[Get started free](/signup) Match Compare live roles against your current evidence. Position Turn proof projects into role-specific applications. Improve Use market feedback to keep the skill plan current. [Return to navigation](#main-navigation)