Engineer II, Conjugation Development and Manufacturing at Vaxcyte

Department: Conjugation

Compensation

$146,000 – $171,000/yr

Setup: On-site
Location: San Carlos, California
Type: Full-time
Level: mid
Posted: Jun 12, 2026

Description

Vaxcyte is hiring an Engineer II for its Conjugation Process Development and Manufacturing group within the CMC organization. The role supports laboratory development, process optimization, cGMP production campaigns, troubleshooting, documentation, and scale-up for multi-valent polysaccharide-based conjugate vaccines. Candidates need a PhD, MS, or BS/BA with the specified years of experience, bioprocess and cGMP knowledge, and proficiency with standard engineering software. The position is onsite five days per week in San Carlos, California, with a salary range of $146,000 to $171,000 in the San Francisco Bay Area.

Required Skills

Bioprocess operations
cGMP principles
Process scale-up
JMP
Troubleshooting
Change control

Additional Information

Minimum Education: PhD, MS, or BS/BA in Chemical Engineering, Biochemical Engineering, Chemistry, Biology, or a related discipline
Required Previous Experiences: 2-5 years of experience for PhD candidates, at least 7 years for MS candidates, and at least 10 years for BS/BA candidates
Practical bioprocess operations experience at bench, pilot, or manufacturing scale
Preferred Qualifications: Experience in late-stage development
Translation Company Name: Vaxcyte

About Vaxcyte

Vaxcyte

vaccine innovationSan Carlos, CA

Vaxcyte is a clinical-stage vaccine innovation company dedicated to eliminating bacterial infections, including invasive pneumococcal disease, Group A Strep and Shigella. Its approach uses advanced chemistry and modern synthetic techniques, including a cell-free protein synthesis platform, to produce vaccines. Vaxcyte says it is investing up to $1 billion in expanding U.S. manufacturing, with new vaccine production in North Carolina.