Lead at Pioneering Intelligence

Compensation

$216,000 – $297,000/yr

Location: Cambridge, Minnesota
Type: Full-time
Level: Lead
Posted: Jun 30, 2026

Description

Pioneering Intelligence is looking for a Lead to drive biological reasoning efforts, focusing on developing multi-modal, multi-scale reasoning engines for biology. This role involves shaping technical and application-level initiatives, guiding model architecture, translating biological insights into model requirements, and integrating reasoning engines into an AI Scientist platform. The Lead will also source use cases, communicate impact, and contribute to discovering new biology.

Required Skills

LLMs
Multimodal Modeling
Representation Learning
Fine-Tuning
Post-Training
Benchmarking
ML Systems
Computational Biology
AI-for-Biology
Translational Data Science
Biological Foundation Models
Scientific Discovery Platforms

Additional Information

Required Previous Experiences: Experience in biotech, pharma, AI-for-science, AI drug discovery, venture creation, or a platform organization serving multiple scientific programs.
Experience deploying AI/ML for biology systems into scientific workflows at enterprise scale.
Experience with LLMs, biological foundation models, protein language models, genomic foundation models, scientific agents, or AI discovery platforms.
Experience working across multiple internal and external customers, therapeutic programs, or discovery teams.
Preferred Qualifications: Demonstrated ability to work with scientists or biotech teams to scope high-value use cases, identify data assets, define success criteria, and translate discovery needs into technical execution plans.
Strong judgment around mechanism-of-action reasoning, target discovery, perturbation biology, scientific credibility, model limitations, hallucination risk, interpretability, and validation.
Experience leading small, high-caliber technical teams through ambiguous scientific or product problems.
Ability to communicate clearly with ML researchers, data engineers, portfolio-company scientists, executives, and venture creation leaders.
Comfort operating in an entrepreneurial environment where the goal is not only to build a model, but to create a new capability that can reshape company creation and scientific discovery.