Skip to main content

Principal Machine Learning Operations Engineer at Definitive Healthcare, US

Department: Product & Engineering

Compensation · Listed in posting

$158,000 – $294,000/yr

Location
Framingham, Massachusetts
Type
Full-time
Level
staff+
Posted

Description

Definitive Healthcare is hiring a Principal MLOps Engineer & Functional Lead to architect, build, and scale machine learning and generative AI infrastructure at enterprise scale. The role covers ML and data pipelines, CI/CD, model deployment, feature and vector stores, workflow orchestration, LLM and RAG infrastructure, model training and fine-tuning, inference optimization, model registries, monitoring, and AWS autoscaling. As functional lead, the person will set engineering standards, architectural guidance, and operational SLAs while mentoring senior engineers. The position requires a relevant bachelor’s or master’s degree, 12+ years of data or ML engineering experience including at least 5 years in production MLOps, hands-on Databricks and AWS experience, and strong Python, TensorFlow, and PyTorch expertise. Base compensation is $158,000–$294,000 per year, with medical, dental, vision, paid time off, and 401(k) benefits.

For job seekers

Ready to find a role that actually fits?

Upload your résumé, start a Job Search Thread, and let Metaintro rank real openings against your experience — then guide you from search to offer.

Match

Compare live roles against your current evidence.

Position

Turn proof projects into role-specific applications.

Improve

Use market feedback to keep the skill plan current.

Return to navigation